Article
Using a pericentromeric interspersed repeat to recapitulate the phylogeny and expansion of human centromeric segmental duplications.
Molecular biology and evolution - 1 Sept 2003
Horvath J E, Gulden C L, Bailey J A, Yohn C, McPherson J D, Prescott A, Roe B A, de Jong P J, Ventura M, Misceo D, Archidiacono N, Zhao S, Schwartz S, Rocchi M, Eichler E E
Abstract excerpt
Despite considerable advances in sequencing of the human genome over the past few years, the organization and evolution of human pericentromeric regions have been difficult to resolve. This is due, in part, to the presence of large, complex blocks of duplicated genomic sequence at the boundary between centromeric satellite and unique euchromatic DNA. Here, we report the identification and characterization of an...
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