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Article

Analysis of primate genomic variation reveals a repeat-driven expansion of the human genome.

Genome research - 1 Mar 2003

Liu Ge, Zhao Shaying, Bailey Jeffrey A, Sahinalp S Cenk, Alkan Can, Tuzun Eray, Green Eric D, Eichler Evan E

Abstract excerpt

We performed a detailed analysis of both single-nucleotide and large insertion/deletion events based on large-scale comparison of 10.6 Mb of genomic sequence from lemur, baboon, and chimpanzee to human. Using a human genomic reference, optimal global alignments were constructed from large (>50-kb) genomic sequence clones. These alignments were examined for the pattern, frequency, and nature of mutational events....

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Identifiers

PMID: 12618366
DOI: 10.1101/gr.923303
PMCID: PMC430288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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