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Article

Large-scale variation among human and great ape genomes determined by array comparative genomic hybridization.

Genome research - 1 Mar 2003

Locke Devin P, Segraves Richard, Carbone Lucia, Archidiacono Nicoletta, Albertson Donna G, Pinkel Daniel, Eichler Evan E

Abstract excerpt

Large-scale genomic rearrangements are a major force of evolutionary change and the ascertainment of such events between the human and great ape genomes is fundamental to a complete understanding of the genetic history and evolution of our species. Here, we present the results of an evolutionary analysis utilizing array comparative genomic hybridization (array CGH), measuring copy-number gains and losses among...

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Identifiers

PMID: 12618365
DOI: 10.1101/gr.1003303
PMCID: PMC430292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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