Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Parallel functional changes in the digestive RNases of ruminants and colobines by divergent amino acid substitutions.

Molecular biology and evolution - 1 Aug 2003

Zhang Jianzhi

Abstract excerpt

A morphological or physiological trait may appear multiple times in evolution. At the molecular level, similar protein functions may emerge independently in different lineages. Whether these parallel functional changes are due to parallel amino acid substitutions has been a subject of debate. Here, I address this question using digestive ribonucleases (RNases) of two groups of foregut-fermenting mammals: ruminant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Mutagenesis, Site-Directed
Share to Primates

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ribonuclease, Pancreatic

Share to Ribonucleases

Share to Ruminants

Share to Selection, Genetic

Share to Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 12777504
DOI: 10.1093/molbev/msg143

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Parallel functional changes in the digestive RNases of ruminants and colobines by divergent amino acid substitutions.PMID 12777504Read ↗

Comparative functional analysis of ribonuclease 1 homologs: molecular insights into evolving vertebrate physiologySemantic proximity Read ↗

Complementary advantageous substitutions in the evolution of an antiviral RNase of higher primates.Semantic proximity Read ↗

Recurrent loss-of-function mutations reveal costs to OAS1 antiviral activity in primatesSemantic proximity Read ↗

Episodic adaptive evolution of primate lysozymes.Semantic proximity Read ↗

Whole-genome sequencing of the snub-nosed monkey provides insights into folivory and evolutionary history.Semantic proximity Read ↗

Rapid evolution of a unique family of primate ribonuclease genes.Semantic proximity Read ↗

RNase 1 genes from the family Sciuridae define a novel rodent ribonuclease cluster.Semantic proximity Read ↗

Evolution of the primate trypanolytic factor APOL1.Semantic proximity Read ↗

Patterns of divergence during evolution of alpha 1-proteinase inhibitors in mammals.Semantic proximity Read ↗

Functional analyses of carnivorous plant-specific amino acid residues in S-like ribonucleases.Semantic proximity Read ↗

Positive Darwinian selection after gene duplication in primate ribonuclease genesSemantic proximity Read ↗

Hominids adapted to metabolize ethanol long before human-directed fermentation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.