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Article

Positive Darwinian selection after gene duplication in primate ribonuclease genes

31 Mar 1998

Abstract excerpt

Evolutionary mechanisms of origins of new gene function have been a subject of long-standing debate. Here we report a convincing case in which positive Darwinian selection operated at the molecular level during the evolution of novel function by gene duplication. The genes for eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN) in primates belong to the ribonuclease gene family, and the ECP...

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PMID: 9520431
DOI: 10.1073/pnas.95.7.3708

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