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Article

Hominids adapted to metabolize ethanol long before human-directed fermentation.

Proceedings of the National Academy of Sciences of the United States of America - 13 Jan 2015

Carrigan Matthew A, Uryasev Oleg, Frye Carole B, Eckman Blair L, Myers Candace R, Hurley Thomas D, Benner Steven A

Abstract excerpt

Paleogenetics is an emerging field that resurrects ancestral proteins from now-extinct organisms to test, in the laboratory, models of protein function based on natural history and Darwinian evolution. Here, we resurrect digestive alcohol dehydrogenases (ADH4) from our primate ancestors to explor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25453080
DOI: 10.1073/pnas.1404167111
PMCID: PMC4299227

Genes

ADH4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25453080-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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