Article
Feedback control of glucocorticoid production is established during fetal development.
Molecular medicine (Cambridge, Mass.) - 1 Nov 1996
Reichardt H M, Schütz G
Abstract excerpt
BACKGROUND: Glucocorticoids are involved in the regulation of metabolic, immunological, and developmental processes. Their synthesis is tightly controlled by feedback regulation through the hypothalamus-pituitary-adrenal (HPA) axis, allowing the organism to respond to stress in an adequate manner...
Topics
- Animals
- Arginine Vasopressin
- Brain
- Corticotropin-Releasing Hormone
- Feedback
- Fetus
- Gene Expression Regulation, Developmental
- Genotype
- Glucocorticoids
- Histocytochemistry
- In Situ Hybridization
- Mice
- Mice, Transgenic
- Pro-Opiomelanocortin
- RNA, Messenger
- Receptors, Glucocorticoid
- Receptors, Mineralocorticoid
- Transcription, Genetic