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Article

Charged assembly helix motif in murine leukemia virus capsid: an important region for virus assembly and particle size determination.

Journal of virology - 1 Jun 2003

Cheslock Sara Rasmussen, Poon Dexter T K, Fu William, Rhodes Terence D, Henderson Louis E, Nagashima Kunio, McGrath Connor F, Hu Wei-Shau

Abstract excerpt

We have identified a region near the C terminus of capsid (CA) of murine leukemia virus (MLV) that contains many charged residues. This motif is conserved in various lengths in most MLV-like viruses. One exception is that spleen necrosis virus (SNV) does not contain a well-defined domain of charged residues. When 33 amino acids of the MLV motif were deleted to mimic SNV CA, the resulting mutant produced...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 12768025
DOI: 10.1128/jvi.77.12.7058-7066.2003
PMCID: PMC156152

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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