Matrix protein of Akv murine leukemia virus: genetic mapping of regions essential for particle formation.

doi:10.1128/JVI.66.7.4479-4487.1992

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Article

Matrix protein of Akv murine leukemia virus: genetic mapping of regions essential for particle formation.

Journal of virology - 1 Jul 1992

Jørgensen E C, Pedersen F S, Jørgensen P

Abstract excerpt

Type C retroviruses assemble at the plasma membrane of the infected cell. Attachment of myristic acid to the N terminus of the Gag precursor polyprotein has been shown to be essential for membrane localization and virus morphogenesis. Here, we report that the matrix (MA) protein contains regions that in conjunction with myristylation are important for Gag protein stability and the assembly of murine leukemia...

Topics

Amino Acid Sequence
Base Sequence
Chromosome Mapping
Cloning, Molecular
DNA Replication
DNA, Viral
Gene Products, gag
Genes, Viral
Genetic Complementation Test
Kinetics
Leukemia Virus, Murine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Myristic Acid

Myristic Acids

Proviruses

Sequence Alignment

Transcription, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 1318415
DOI: 10.1128/JVI.66.7.4479-4487.1992
PMCID: PMC241257

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1318415-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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