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Article

Genetic context modulates aging and degeneration in the murine retina

20 Jan 2025

Abstract excerpt

BACKGROUND: Age is the principal risk factor for neurodegeneration in both the retina and brain. The retina and brain share many biological properties; thus, insights into retinal aging and degeneration may shed light onto similar processes in the brain. Genetic makeup strongly influences susceptibility to age-related retinal disease. However, studies investigating retinal aging have not sufficiently accounted...

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PMID: 39833899
DOI: 10.1186/s13024-025-00800-9

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