Article
A QTL on distal chromosome 3 that influences the severity of light-induced damage to mouse photoreceptors.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jun 2000
Danciger M, Matthes M T, Yasamura D, Akhmedov N B, Rickabaugh T, Gentleman S, Redmond T M, La Vail M M, Farber D B
Abstract excerpt
C57BL/6J-c(2J) (c2J) albino mice showed much less damage to their photoreceptors after exposure to prolonged light than BALB/c mice and seven other albino strains tested. There were no gender differences, and preliminary studies suggested that the c2J relative protective effect was a complex trait. A genome-wide scan using dinucleotide repeat markers was carried out for the analysis of 194 progeny of the...
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