Article
Quantitative genetics of age-related retinal degeneration: a second F1 intercross between the A/J and C57BL/6 strains.
Molecular vision - 25 Jan 2007
Danciger M, Yang H, Ralston R, Liu Y, Matthes M T, Peirce J, Lavail M M
Abstract excerpt
PURPOSE: Previously, several quantitative trait loci (QTL) that influence age-related retinal degeneration (ageRD) were demonstrated in a cross between the C57BL/6J-c(2J) and BALB/cByJ strains (B x C). In this study, as a complementary approach to ongoing recombinant progeny testing for the purpose of identifying candidate quantitative trait genes (QTG), a second test cross using the A/J and the pigmented...
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