Article
Microsatellite DNA polymorphism of human adrenomedullin gene in type 2 diabetic patients with renal failure.
Kidney international - 1 Jun 2003
Ishimitsu Toshihiko, Tsukada Kohju, Minami Junichi, Ono Hidehiko, Ohrui Masami, Hino Jun, Kangawa Kenji, Matsuoka Hiroaki
Abstract excerpt
BACKGROUND: Adrenomedullin (AM) is a hypotensive peptide widely produced in the cardiovascular organs and tissues such as the heart, kidney, and the vascular cells. We have previously cloned and sequenced the genomic DNA encoding human AM gene, and determined that the gene is located in the short arm of chromosome 11. The 3'-end of the gene is flanked by the microsatellite marker of cytosine adenine (CA) repeats....
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