Article
Blood pressure and urinary sodium excretion in relation to the A-1984G adrenomedullin polymorphism in a Chinese population.
Kidney international - 1 Apr 2006
Li Y, Staessen J A, Li L-H, Gao P-J, Thijs L, Brand E, Brand-Herrmann S M, Zhu D-L, Wang J-G
Abstract excerpt
Adrenomedullin (ADM) is a vasodilator and inhibits salt appetite. An A-to-G substitution at position -1984 in the promoter region of the ADM gene likely increases transcription. We therefore investigated this polymorphism in relation to blood pressure and urinary sodium in a Chinese population. We genotyped 427 Chinese enrolled in a family-based population study. We measured blood pressure by conventional...
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