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Plasma Adrenomedullin and Allelic Variation in the ADM Gene and Kidney Disease in People With Type 2 Diabetes.

Diabetes - 1 Sept 2015

Velho Gilberto, Ragot Stéphanie, Mohammedi Kamel, Gand Elise, Fraty Mathilde, Fumeron Frédéric, Saulnier Pierre-Jean, Bellili-Munoz Naima, Bouby Nadine, Potier Louis, Alhenc-Gelas François, Marre Michel, Hadjadj Samy, Roussel Ronan

Abstract excerpt

Production of adrenomedullin (ADM), a vasodilator peptide, increases in response to ischemia and hypoxia in the vascular wall and the kidney. This may be an adaptive response providing protection against organ damage. We investigated the hypothesis that ADM has a nephroprotective effect in two prospective cohorts of patients with type 2 diabetes recruited in France. The highest tertile of plasma MR-proADM (a...

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Creatinine
Diabetes Mellitus, Type 2
Diabetic Nephropathies
Glomerular Filtration Rate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Kidney Failure, Chronic

Peptide Fragments

Protein Precursors

Renal Insufficiency, Chronic

Source

Identifiers

PMID: 25948679
DOI: 10.2337/db14-1852

Genes

ADM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Plasma Adrenomedullin and Allelic Variation in the ADM Gene and Kidney Disease in People With Type 2 Diabetes.PMID 25948679Read ↗

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