Article
A pilot study on genetic variation in purine-rich elements in the nephrin gene promoter in type 2 diabetic patients.
Biological research - 1 Jan 2007
González Rodrigo, Tirado Ares, Balanda Monserrat, Alvo Miriam, Barquín Inés, Durruty Pilar, Lobos Sergio, Seelenfreund Daniela
Abstract excerpt
Diabetic nephropathy (DN) is one of the major complications of type 2 diabetes and is associated with coronary disease. Nephrin, a protein mainly expressed in glomeruli, is decreased in DN and other kidney diseases. Since insulin levels are misregulated in type 2 diabetes, a possible connection b...
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