Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A pilot study on genetic variation in purine-rich elements in the nephrin gene promoter in type 2 diabetic patients.

Biological research - 1 Jan 2007

González Rodrigo, Tirado Ares, Balanda Monserrat, Alvo Miriam, Barquín Inés, Durruty Pilar, Lobos Sergio, Seelenfreund Daniela

Abstract excerpt

Diabetic nephropathy (DN) is one of the major complications of type 2 diabetes and is associated with coronary disease. Nephrin, a protein mainly expressed in glomeruli, is decreased in DN and other kidney diseases. Since insulin levels are misregulated in type 2 diabetes, a possible connection between DN and its decreased nephrin expression could be the presence of regulatory elements responsive to insulin in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetic Nephropathies

Share to Genetic Markers

Share to Membrane Proteins

Share to Pilot Projects

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 18449463
DOI: /S0716-97602007000400010

Genes

NPHS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A pilot study on genetic variation in purine-rich elements in the nephrin gene promoter in type 2 diabetic patients.PMID 18449463Read ↗

Analysis of the intronic single nucleotide polymorphism rs#466452 of the nephrin gene in patients with diabetic nephropathy.Semantic proximity Read ↗

Association of nephrin gene polymorphisms with type 2 diabetes in a Japanese population: The Funagata study.Semantic proximity Read ↗

Rare functional variants of podocin (NPHS2) promoter in patients with nephrotic syndrome.Semantic proximity Read ↗

A potentially functional polymorphism in the regulatory region of let-7a-2 is associated with an increased risk for diabetic nephropathy.Semantic proximity Read ↗

Polymorphisms in the nephrin gene and diabetic nephropathy in type 1 diabetic patients.Semantic proximity Read ↗

A novel polymorphism in the aldose reductase gene promoter region is strongly associated with diabetic retinopathy in adolescents with type 1 diabetes.Semantic proximity Read ↗

Microsatellite DNA polymorphism of human adrenomedullin gene in type 2 diabetic patients with renal failure.Semantic proximity Read ↗

Functional analysis of promoter mutations in the ACTN4 and SYNPO genes in focal segmental glomerulosclerosis.Semantic proximity Read ↗

A single nucleotide polymorphism at position --109 of the RANTES proximal promoter.Semantic proximity Read ↗

Analysis of the HNF4 alpha gene in Caucasian type II diabetic nephropathic patients.Semantic proximity Read ↗

Investigation of the human ANP gene in type 1 diabetic nephropathy: case-control and follow-up studies.Semantic proximity Read ↗

Association of an Osteopontin gene promoter polymorphism with susceptibility to diabetic nephropathy in Asian Indians.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.