Article
Characterization of the hyperrecombination phenotype of the pol3-t mutation of Saccharomyces cerevisiae.
Genetics - 1 May 2003
Galli Alvaro, Cervelli Tiziana, Schiestl Robert H
Abstract excerpt
The DNA polymerase delta (Pol3p/Cdc2p) allele pol3-t of Saccharomyces cerevisiae has previously been shown to increase the frequency of deletions between short repeats (several base pairs), between homologous DNA sequences separated by long inverted repeats, and between distant short repeats, increasing the frequency of genomic deletions. We found that the pol3-t mutation increased intrachromosomal recombination...
Topics
- DNA Polymerase III
- DNA Repair Enzymes
- DNA-Binding Proteins
- Endonucleases
- Gamma Rays
- Mutation
- Rad52 DNA Repair and Recombination Protein
- Recombination, Genetic
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Ultraviolet Rays