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Article

The essential helicase gene RAD3 suppresses short-sequence recombination in Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Aug 1995

Bailis A M, Maines S, Negritto M T

Abstract excerpt

We have isolated an allele of the essential DNA repair and transcription gene RAD3 that relaxes the restriction against recombination between short DNA sequences in Saccharomyces cerevisiae. Double-strand break repair and gene replacement events requiring recombination between short identical or mismatched sequences were stimulated in the rad3-G595R mutant cells. We also observed an increase in the physical...

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Identifiers

PMID: 7623796
DOI: 10.1128/MCB.15.8.3998
PMCID: PMC230639

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