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Article

Inherited genetic susceptibility to breast cancer: the beginning of the end or the end of the beginning?

The American journal of pathology - 1 Oct 2013

Ghoussaini Maya, Pharoah Paul D P, Easton Douglas F

Abstract excerpt

Genome-wide association studies have identified 72 loci associated with breast cancer susceptibility. Seventeen of these are known to predispose to other cancers. High-penetrance susceptibility loci for breast cancer usually result from coding alterations, principally in genes involved in DNA repair, whereas almost all of the associations identified through genome-wide association studies are found in noncoding...

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Identifiers

PMID: 23973388
DOI: 10.1016/j.ajpath.2013.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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