Comparison of standard PCR and the LightCycler technique to determine the thrombophilic mutations: an efficiency and cost study.

Abstract excerpt

For several years it has been possible to routinely detect numerous mutations in the human genome by different methods. The most common technique is a standard PCR, but real time fluorescence PCR is increasingly being used. The purpose of this paper is to compare these two different techniques from the point of view of reliability, time consumption, and cost. More than 600 DNA samples of prevalence studies and...

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