Article
Identification of three genetic risk factors for venous thrombosis using a multiplex allele-specific PCR assay: comparison of conventional and new alternative methods for the preparation of DNA from clinical samples.
Journal of thrombosis and thrombolysis - 1 Dec 2003
Angelini Antonio, Di Febbo Concetta, Baccante Giovanna, Di Nisio Marcello, Di Ilio Carmine, Cuccurullo Franco, Porreca Ettore
Abstract excerpt
The demand for thrombophilia testing at the molecular level is increasing and with it the need for a simple and rapid and cost-saving procedure for the preparation of genomic DNA from whole blood samples. The aim of this paper is to compare the efficiency of two conventional commercial procedures (Genomic, Eurobio-Labtek, and Nucleospin, Macherey-Nagel) and two our alternative approaches (microwave irradiation...
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