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Article

Enhanced long-term potentiation in the hippocampus of rats expressing mutant presenillin-1 is age related.

Neurobiology of disease - 1 Apr 2003

Pybus Ruth, Barnard Eleanor, Estibeiro Peter, Mullins John, MacLeod Nikki

Abstract excerpt

Electrophysiological recordings were made from Fischer rats engineered to express the human presenilin 1 gene carrying the M146V mutation. Extracellular recordings of field excitatory post-synaptic potential (EPSPs) were made to investigate EPSP properties, paired pulse responses, posttetanic potentiation, and long-term potentiation in the stratum radiatum and dentate gyrus of hippocampal slices maintained in...

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Identifiers

PMID: 12742741
DOI: 10.1016/s0969-9961(03)00016-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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