Article
A neutral explanation for the correlation of diversity with recombination rates in humans.
American journal of human genetics - 1 Jun 2003
Hellmann Ines, Ebersberger Ingo, Ptak Susan E, Pääbo Svante, Przeworski Molly
Abstract excerpt
One of the most striking findings to emerge from the study of genomic patterns of variation is that regions with lower recombination rates tend to have lower levels of intraspecific diversity but not of interspecies divergence. This uncoupling of variation within and between species has been widely interpreted as evidence that natural selection shapes patterns of genetic variability genomewide. We revisited the...
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