Article
Human population differentiation is strongly correlated with local recombination rate.
PLoS genetics - 26 Mar 2010
Keinan Alon, Reich David
Abstract excerpt
Allele frequency differences across populations can provide valuable information both for studying population structure and for identifying loci that have been targets of natural selection. Here, we examine the relationship between recombination rate and population differentiation in humans by analyzing two uniformly-ascertained, whole-genome data sets. We find that population differentiation as assessed by...
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