Article
The influence of recombination on human genetic diversity.
PLoS genetics - 22 Sept 2006
Spencer Chris C A, Deloukas Panos, Hunt Sarah, Mullikin Jim, Myers Simon, Silverman Bernard, Donnelly Peter, Bentley David, McVean Gil
Abstract excerpt
In humans, the rate of recombination, as measured on the megabase scale, is positively associated with the level of genetic variation, as measured at the genic scale. Despite considerable debate, it is not clear whether these factors are causally linked or, if they are, whether this is driven by the repeated action of adaptive evolution or molecular processes such as double-strand break formation and mismatch...
Topics
Join the communities discussing this publication.