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Article

Schizophrenia is not associated with DRD4 48-base-pair-repeat length or individual alleles: results of a meta-analysis.

Biological psychiatry - 15 Sept 2003

Glatt Stephen J, Faraone Stephen V, Tsuang Ming T

Abstract excerpt

BACKGROUND: The gene DRD4, coding for dopamine receptor D4, was considered a candidate for association with schizophrenia based on its upregulation in postmortem schizophrenic brain and affinity for clozapine. Many studies sought allelic association of a 48-base-pair repeat in DRD4 exon 3 with schizophrenia, but found no strong evidence for a relationship. The present work sought to determine if this observation...

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Source

Identifiers

PMID: 13129658
DOI: 10.1016/s0006-3223(03)00180-x

Genes

DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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Schizophrenia is not associated with DRD4 48-base-pair-repeat length or individual alleles: results of a meta-analysis.PMID 13129658Read ↗

Dopamine D4 receptor gene (DRD4) variants and schizophrenia: meta-analyses.Semantic proximity Read ↗

Repeat length variation in the dopamine D4 receptor gene shows no evidence of association with schizophrenia.Semantic proximity Read ↗

Dopamine D4 receptor variants in Chinese sporadic and familial schizophrenics.Semantic proximity Read ↗

Dopamine D4 receptor 48-bp repeat polymorphism: no association with response to antipsychotic treatment, but association with catatonic schizophrenia.Semantic proximity Read ↗

Association between different psychotic disorders and the DRD4 polymorphism, but no differences in the main ligand binding region of the DRD4 receptor protein compared to controls.Semantic proximity Read ↗

Multiple dopamine D4 receptor variants in the human population.Semantic proximity Read ↗

Dopamine D4 and D5 receptor gene variant effects on clozapine response in schizophrenia: replication and exploration.Semantic proximity Read ↗

Lack of association between dopamine D4 receptor gene and schizophrenia.Semantic proximity Read ↗

Twelve-nucleotide repeat polymorphism of D4 dopamine receptor gene in Chinese familial schizophrenic patients.Semantic proximity Read ↗

A hypervariable segment in the human dopamine receptor D4 (DRD4) gene.Semantic proximity Read ↗

Allelic variation in the D4 dopamine receptor (DRD4) gene does not predict response to clozapine.Semantic proximity Read ↗

No association between SLC6A2, SLC6A3, DRD2 polymorphisms and schizophrenia in the Han Chinese population.Semantic proximity Read ↗

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