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Article

Neurotrophins and neurodegenerative diseases: receptors stuck in traffic?

Journal of neuropathology and experimental neurology - 1 Apr 2003

Kruttgen Alex, Saxena Smita, Evangelopoulos Maria Eleptheria, Weis Joachim

Abstract excerpt

Neurotrophins are well known for their physiological role as key modulators of neuronal survival, neurite out-growth, and synaptic connectivity during development and into adulthood. Moreover, neurotrophins are potent agents, ameliorating neuronal degeneration in many model systems for neurological diseases. However, a causal role for mutations in neurotrophins or neurotrophin receptors in human neurodegenerative...

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Identifiers

PMID: 12722826
DOI: 10.1093/jnen/62.4.340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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