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Article

Gene transduction efficiency and maturation status in mouse bone marrow-derived dendritic cells infected with conventional or RGD fiber-mutant adenovirus vectors.

Cancer gene therapy - 1 May 2003

Okada Naoki, Masunaga Yasushige, Okada Yuka, Iiyama Sayaka, Mori Naoki, Tsuda Takashi, Matsubara Asako, Mizuguchi Hiroyuki, Hayakawa Takao, Fujita Takuya, Yamamoto Akira

Abstract excerpt

Since dendritic cells (DCs) play a critical role in establishing antigen-specific adaptive immune responses, in the past several years, therapeutic strategies using genetically modified DCs against cancer and infectious diseases have attracted increasing attention. In the present study, we demonstrated that RGD fiber-mutant adenovirus vector (AdRGD) exhibited markedly superior gene transduction efficiency in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12719712
DOI: 10.1038/sj.cgt.7700586

Genes

CCR6
CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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