Article
[Efficient gene delivery into dendritic cells by fiber-mutant adenovirus vectors].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan - 1 Aug 2001
Okada N
Abstract excerpt
Dendritic cells (DC) are professional antigen-presenting cells with a key function in the immune system as initiators of T-cell responses against microbial pathogens and tumors. Therefore, the immunization using DC loaded with tumor-associated antigens is potential to represent a powerful method of inducing anti-tumor immunity. Recent studies have demonstrated the usefulness of DC genetically modified by...
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