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Article

Ex vivo induction of multiple myeloma-specific cytotoxic T lymphocytes.

Blood - 15 Aug 2003

Hayashi Toshiaki, Hideshima Teru, Akiyama Masaharu, Raje Noopur, Richardson Paul, Chauhan Dharminder, Anderson Kenneth C

Abstract excerpt

Multiple myeloma (MM) is an incurable plasma cell malignancy characterized by immunosuppression. In this study, we identified factors in patients' bone marrow (BM) sera inhibiting autologous anti-MM immunity and developed an ex vivo strategy for inducing MM-specific cytotoxic T lymphocytes (CTLs). We found that sera from BM of MM patients inhibited induction of dendritic cells (DCs), evidenced by both phenotype...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Granulocyte-Macrophage Colony-Stimulating Factor

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Share to T-Lymphocytes, Cytotoxic

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Source

Identifiers

PMID: 12714512
DOI: 10.1182/blood-2002-09-2828

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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