Article
Autologous antitumor activity by NK cells expanded from myeloma patients using GMP-compliant components.
Blood - 15 Mar 2008
Alici Evren, Sutlu Tolga, Björkstrand Bo, Gilljam Mari, Stellan Birgitta, Nahi Hareth, Quezada Hernan Concha, Gahrton Gösta, Ljunggren Hans-Gustaf, Dilber M Sirac
Abstract excerpt
Multiple myeloma (MM) is an incurable plasma cell malignancy with poor outcome. The most promising therapeutic options currently available are combinations of transplantation, targeted pharmacotherapy, and immunotherapy. Cell-based immunotherapy after hematopoietic stem-cell transplantation has been attempted, but with limited efficacy. Natural killer (NK) cells are interesting candidates for new means of...
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