Article

Molecular mechanisms promoting long-term cytopenia after BCMA CAR-T therapy in Multiple Myeloma

2024-05-22

Abstract excerpt

<h4>ABSTRACT</h4> Hematological toxicity is a common side effect of CAR-T therapies, being particularly severe in relapsed/refractory multiple myeloma (MM) patients. In this study, we analyzed a cohort of 48 patients treated with BCMA CAR-T cells to characterize the kinetics of cytopenia, identify predictive factors and determine potential mechanism underlying these toxicities. The overall incidence of cytopenia w...

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Literature Corpus work: 1322c9c5-05a4-5b0c-a3ec-cee86edace6e
DOI: 10.1101/2024.05.22.24307750

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