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Article

IL-10 and TNF-alpha polymorphisms in a sample of Sicilian patients affected by tuberculosis: implication for ageing and life span expectancy.

Mechanisms of ageing and development - 1 Apr 2003

Scola Letizia, Crivello Antonio, Marino Vincenzo, Gioia Vito, Serauto Alberto, Candore Giuseppina, Colonna-Romano Giuseppina, Caruso Calogero, Lio Domenico

Abstract excerpt

Human longevity seems to be directly correlated with optimal functioning of the immune system, suggesting that some genetic determinants of longevity might reside in those polymorphisms for the immune system genes that regulate immune responses, in particular cytokine gene polymorphisms. In fact, modification of cytokine network is a constant report in studies on age related modification of immune response....

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PMID: 12714269
DOI: 10.1016/s0047-6374(03)00038-1

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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