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Article

Association between longevity and cytokine gene polymorphisms. A study in Sardinian centenarians.

Aging clinical and experimental research - 1 Jun 2004

Pes Giovanni Mario, Lio Domenico, Carru Ciriaco, Deiana Luca, Baggio Giovannella, Franceschi Claudio, Ferrucci Luigi, Oliveri Fabiola, Scola Letizia, Crivello Antonio, Candore Giuseppina, Colonna-Romano Giuseppina, Caruso Calogero

Abstract excerpt

BACKGROUND AND AIMS: Human longevity seems to be directly correlated with optimal functioning of the immune system, suggesting that some genetic determinants of longevity reside in those polymorphisms for the immune system genes which regulate immune-inflammatory responses, in particular cytokine gene polymorphisms. The frequency of -174C single nucleotide polymorphism (SNP) in the promoter region of the...

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PMID: 15462469
DOI: 10.1007/BF03327391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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