Article
Role of homologous recombination in carcinogenesis.
Experimental and molecular pathology - 1 Apr 2003
Bishop Alexander J R, Schiestl Robert H
Abstract excerpt
Cancer develops when cells no longer follow their normal pattern of controlled growth. In the absence or disregard of such regulation, resulting from changes in their genetic makeup, these errant cells acquire a growth advantage, expanding into precancerous clones. Over the past decade many studies have revealed the relevance of genomic mutation in this process, be it by misreplication, environmental damage, or a...
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