Article
The role of DNA repair by homologous recombination in oncogenesis.
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi - 1 Jan 2000
Bordeianu Gabriela, Zugun-Eloae F, Rusu M G
Abstract excerpt
DNA repair by homologous recombination (HR) may be regarded as the two faces of a coin: lowering the oncogenetic potential (precise repair with no consequences on genomic status) or increasing it (deleterious action which may determine chromosome rearrangements such as loss of heterozigosity). Inherited mutations in genes involved in HR are associated with gene rearrangement and may be a prerequisite for tumor...
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