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Article

Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 Tax expressing cells.

Molecular and cellular biochemistry - 1 Mar 2003

de la Fuente Cynthia, Wang Lai, Wang Dai, Deng Longwen, Wu Kaili, Li Hong, Stein L Dana, Denny Thomas, Coffman Frederick, Kehn Kylene, Baylor Shanese, Maddukuri Anil, Pumfery Anne, Kashanchi Fatah

Abstract excerpt

Adult T-cell leukemia (ATL) and HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP) are associated with Human T-cell lymphotropic virus type 1 (HTLV-1) infection. The viral transactivator, Tax is able to mediate the cell cycle progression by targeting key regulators of the cell cycle such as p21/waf1, p16/ink4a, p53, cyclins D1-3/cdk complexes, and the mitotic spindle checkpoint MAD apparatus,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12708749
DOI: 10.1023/a:1022866027585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Paradoxical effects of a stress signal on pro- and anti-apoptotic machinery in HTLV-1 Tax expressing cells.PMID 12708749Read ↗

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