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Article

Gene expression time-series analysis of camptothecin effects in U87-MG and DBTRG-05 glioblastoma cell lines.

Molecular cancer - 11 Aug 2008

Morandi Elena, Severini Cinzia, Quercioli Daniele, D'Ario Giovanni, Perdichizzi Stefania, Capri Miriam, Farruggia Giovanna, Mascolo Maria Grazia, Horn Wolfango, Vaccari Monica, Serra Roberto, Colacci Annamaria, Silingardi Paola

Abstract excerpt

BACKGROUND: The clinical efficacy of camptothecin (CPT), a drug specifically targeting topoisomerase I (TopoI), is under evaluation for the treatment of malignant gliomas. Due to the high unresponsiveness of these tumours to chemotherapy, it would be very important to study the signalling network...

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Source

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Identifiers

PMID: 18694480
DOI: 10.1186/1476-4598-7-66
PMCID: PMC2556695

Genes

BUB1
BUB3
MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18694480-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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