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Article

Regulation of beta cell glucokinase by S-nitrosylation and association with nitric oxide synthase.

The Journal of cell biology - 28 Apr 2003

Rizzo Megan A, Piston David W

Abstract excerpt

Glucokinase (GK) activity plays a key role in glucose-stimulated insulin secretion from pancreatic beta cells. Insulin regulates GK activity by modulating its association with secretory granules, although little is known about the mechanisms involved in regulating this association. Using quantitative imaging of multicolor fluorescent proteins fused to GK, we found that the dynamic association of GK with secretory...

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Identifiers

PMID: 12707306
DOI: 10.1083/jcb.200301063
PMCID: PMC2172922

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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