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Article

Association of the p53 codon 72 polymorphism with clinicopathological characteristics of colorectal cancer through mRNA analysis.

Oncology reports - 1 Mar 2014

De Oliveira Ligia Petrolini, López Ignacio, Dos Santos Erika Maria Monteiro, Tucci Paula, Marín Mónica, Soares Fernando Augusto, Rossi Benedito Mauro, Coudry Renata De Almeida

Abstract excerpt

TP53 represents a suitable candidate for a colorectal cancer susceptibility locus. The polymorphism in the p53 72nd codon involves a proline to arginine substitution, leading to changes in gene transcription activity, interaction with other proteins and modulation of apoptosis. Studies evaluating the association between this polymorphism and colorectal cancer (CRC) have shown inconsistent results, and none have...

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Identifiers

PMID: 24366026
DOI: 10.3892/or.2013.2940

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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