Article
TP53 codon 72 polymorphism with hepatocellular carcinoma: a metaanalysis.
The Journal of international medical research - 1 Jan 2012
Ding C, Yu H, Yu H, Qin H
Abstract excerpt
OBJECTIVE: The association between codon 72 polymorphism of the tumour protein p53 (TP53) gene - which results in a missense mutation of arginine (R) to proline (P) - and susceptibility to hepatocellular carcinoma (HCC) is controversial. A metaanalysis was performed in order to define this relationship more precisely. METHODS: Published studies of TP53 codon 72 polymorphism and the risk of HCC were identified....
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