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Article

Role of p53 codon 72 polymorphism in chromosomal aberrations and mitotic index in patients with chronic hepatitis B.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Nov 2012

Akbaş H, Yalcin K, Isi H, Tekes S, Atay A E, Akkus Z, Budak T

Abstract excerpt

Polymorphisms of the p53 gene, which participates in DNA repair, can affect the functioning of the p53 protein. The Arg and Pro variants in p53 codon 72 were shown to have different regulation properties of p53-dependent DNA repair target genes that can affect various levels of cytogenetic aberrations in chronic hepatitis B patients. The present study aimed to examine the frequency of chromosomal aberrations and...

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Identifiers

PMID: 22892830
DOI: 10.1590/s0100-879x2012007500129
PMCID: PMC3854153

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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