Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

YB-1 Coordinates Vascular Smooth Muscle α-Actin Gene Activation by Transforming Growth Factor β1 and Thrombin during Differentiation of Human Pulmonary Myofibroblasts

10 Aug 2005

Abstract excerpt

Profibrotic regulatory mechanisms for tissue repair after traumatic injury have developed under strong evolutionary pressure to rapidly stanch blood loss and close open wounds. We have examined the roles played by two profibrotic mediators, transforming growth factor beta1 (TGFbeta1) and thrombin, in directing expression of the vascular smooth muscle alpha-actin (SMalphaA) gene, an important determinant of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Cardiac Fibrosis and Remodeling
Share to TGF-β signaling in diseases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16093352
DOI: 10.1091/mbc.e05-03-0216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

YB-1 Coordinates Vascular Smooth Muscle α-Actin Gene Activation by Transforming Growth Factor β1 and Thrombin during Differentiation of Human Pulmonary MyofibroblastsPMID 16093352Read ↗

Vascular smooth muscle alpha-actin gene transcription during myofibroblast differentiation requires Sp1/3 protein binding proximal to the MCAT enhancer.Semantic proximity Read ↗

Coordinate Transcriptional and Translational Repression of p53 by TGF-β1 Impairs the Stress ResponseSemantic proximity Read ↗

TGF-β-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoformsSemantic proximity Read ↗

Akt1 Mediates α-Smooth Muscle Actin Expression and Myofibroblast Differentiation via Myocardin and Serum Response FactorSemantic proximity Read ↗

Control of the tissue inhibitor of metalloproteinases-1 promoter in culture-activated rat hepatic stellate cells: regulation by activator protein-1 DNA binding proteins.Semantic proximity Read ↗

HuR drives lung fibroblast differentiation but not metabolic reprogramming in response to TGF-β and hypoxiaSemantic proximity Read ↗

Negative regulation of the vascular smooth muscle alpha-actin gene in fibroblasts and myoblasts: disruption of enhancer function by sequence-specific single-stranded-DNA-binding proteins.Semantic proximity Read ↗

ZEB1 Links p63 and p73 in a Novel Neuronal Survival Pathway Rapidly Induced in Response to Cortical IschemiaSemantic proximity Read ↗

P311 induces a TGF-β1–independent, nonfibrogenic myofibroblast phenotypeSemantic proximity Read ↗

Regulation of the tissue factor geneSemantic proximity Read ↗

A molecular mechanism for the differential regulation of TGF-beta1 expression due to the common SNP -509C-T (c. -1347C > T).Semantic proximity Read ↗

P311 induces a TGF-beta1-independent, nonfibrogenic myofibroblast phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.