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Article

The deletion of transforming growth factor-beta-induced myofibroblasts depends on growth conditions and actin organization.

The American journal of pathology - 1 Dec 1999

Arora P D, McCulloch C A

Abstract excerpt

Myofibroblasts are important but transient mediators of normal wound contraction and are characterized phenotypically by their high levels of alpha-smooth-muscle actin (SMA). During wound maturation, these cells disappear. We have examined the mechanisms that lead to myofibroblast deletion in a fibroblast culture model. Transforming growth factor-beta (TGF-beta) was used to increase SMA content in gingival...

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Identifiers

PMID: 10595938
DOI: 10.1016/s0002-9440(10)65527-7
PMCID: PMC1866951

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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