Article
Effect of obesity on HDL and LDL particle sizes in carriers of the null P207L or defective D9N mutation in the lipoprotein lipase gene: the Québec LipD Study.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 May 2003
Ruel I L, Gaudet D, Perron P, Bergeron J, Julien P, Lamarche B
Abstract excerpt
BACKGROUND: We have recently demonstrated that French Canadians bearing a mutation in the lipoprotein lipase (LPL) gene present an impaired lipoprotein-lipid profile characterized by small low-density lipoprotein (LDL) and high-density lipoprotein (HDL) particles compared with healthy subjects. It has also been documented that obesity has a significant impact on HDL and LDL particle sizes. OBJECTIVE: To examine...
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