Article
Visceral obesity attenuates the effect of the hepatic lipase -514C>T polymorphism on plasma HDL-cholesterol levels in French-Canadian men.
Molecular genetics and metabolism - 1 Jan 2003
St-Pierre Julie, Miller-Felix Isabelle, Paradis Marie-Eve, Bergeron Jean, Lamarche Benoît, Després Jean-Pierre, Gaudet Daniel, Vohl Marie-Claude
Abstract excerpt
UNLABELLED: The dyslipidemic state of visceral obesity is characterized by increased plasma triglyceride (TG) levels, low HDL-cholesterol concentrations and alterations in LDL composition and concentration. A functional, non-coding -514C>T single nucleotide polymorphism (SNP) of the hepatic lipase gene (LIPC) has been related to variation in HDL-cholesterol concentrations. OBJECTIVES: To investigate the...
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