Article
Lipoprotein lipase S447X variant associated with VLDL, LDL and HDL diameter clustering in the MetS.
Lipids in health and disease - 19 Aug 2011
Wood Alexis C, Glasser Stephen, Garvey W Timothy, Kabagambe Edmond K, Borecki Ingrid B, Tiwari Hemant K, Tsai Michael Y, Hopkins Paul N, Ordovas Jose M, Arnett Donna K
Abstract excerpt
BACKGROUND: Previous analysis clustered 1,238 individuals from the general population Genetics of Lipid Lowering Drugs Network (GOLDN) study by the size of their fasting very low-density, low-density and high-density lipoproteins (VLDL, LDL, HDL) using latent class analysis. From two of the eight identified groups (N = 251), ~75% of individuals met Adult Treatment Panel III criteria for the metabolic syndrome...
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