Article
Determinants of HDL particle size in patients with the null (P207L) or defective (D9N) mutation in the lipoprotein lipase gene: the Québec LipD Study.
Atherosclerosis - 1 Jun 2002
Ruel Isabelle L, Gaudet Daniel, Perron Patrice, Pascot Agnès, Després Jean Pierre, Bergeron Jean, Julien Pierre, Lamarche Benoît
Abstract excerpt
The aim of the present study was to examine the impact of the defective D9N and the null P207L mutations in the lipoprotein lipase (LPL) gene on high density lipoprotein (HDL) particle size in relation to specific environmental factors such as obesity, gender and menopausal status. Analyses were carried out in 118 heterozygous carriers of the D9N mutation and 88 heterozygous for the P207L mutation. HDL particle...
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