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Article

Gene polymorphisms in the Quebec population: a risk to develop hypertriglyceridemia.

Biochemical and biophysical research communications - 2 Jun 2006

Garenc Christophe, Aubert Samuel, Laroche Jerôme, Bergeron Jean, Gagné Claude, Rousseau François, Julien Pierre

Abstract excerpt

In Eastern Québec, two major lipoprotein lipase (LPL) gene mutations, P207L and G188E, lead to complete LPL deficiency in homozygote subjects and contribute to elevated predisposition to hypertriglyceridemia in heterozygotes. First, we determined the allele frequencies of LPL (D9N, G188E, P207L, D250N, N291S, and S447X), APOE (C112R and C158R), PPARalpha (L162V), and PPARgamma2 (P12A) single nucleotide...

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Source

Identifiers

PMID: 16630553
DOI: 10.1016/j.bbrc.2006.03.187

Genes

LPL
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Gene polymorphisms in the Quebec population: a risk to develop hypertriglyceridemia.PMID 16630553Read ↗

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