Article
Apolipoprotein B-100-containing lipoprotein metabolism in subjects with lipoprotein lipase gene mutations.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2012
Ooi Esther M M, Russell Betsy S, Olson Eric, Sun Sam Z, Diffenderfer Margaret R, Lichtenstein Alice H, Keilson Leonard, Barrett P Hugh R, Schaefer Ernst J, Sprecher Dennis L
Abstract excerpt
OBJECTIVE: We investigated the impact of lipoprotein lipase (LPL) gene mutations on apolipoprotein B (apoB)-100 metabolism. METHODS AND RESULTS: We studied 3 subjects with familial LPL deficiency; 14 subjects heterozygous for the LPL gene mutations Gly188Glu, Trp64Stop, and Ile194Thr; and 10 control subjects. Very-low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), and low-density lipoprotein...
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